[iSpine Admin]

CLINICAL TRIALS

General:

• The myth of lumbar instability: the importance of abnormal loading as a cause of low back pain
• Significantly improved lumbar arthroplasty placement using image guidance: technical note
• Total lumbar disc replacement in athletes: clinical results, return to sport and athletic performance

Activ:

• US Clinical Trial Procedures Underway

Bryan:

• Effects of a cervical disc prosthesis on maintaining sagittal alignment of the functional spinal unit and overall sagittal balance of the cervical spine
• Intervertebral disc replacement for cervical degenerative disease--clinical results and functional outcome at two years in patients implanted with the Bryan cervical disc prosthesis

Charite:

• Effect of age on clinical and radiographic outcomes and adverse events following 1-level lumbar arthroplasty after a minimum 2-year follow-up
• Patient selection for lumbar arthroplasty and arthrodesis: the effect of revision surgery in a controlled, multicenter, randomized study
• Survival and clinical outcome of SB Charite III disc replacement for back pain
• Long-term results of one-level lumbar arthroplasty: minimum 10-year follow-up of the CHARITE artificial disc in 106 patients
• Prevalence of heterotopic ossification following total disc replacement. A prospective, randomized study of two hundred and seventy-six patients
• Polyethylene wear debris and long-term clinical failure of the Charité disc prosthesis: a study of 4 patients
• Revisability of the CHARITE artificial disc replacement: analysis of 688 patients enrolled in the U.S. IDE study of the CHARITE Artificial Disc
• Charité total disc replacement--clinical and radiographical results after an average follow-up of 17 years.
• A prospective, randomized, multicenter food and drug administration Investigational device exemptions study of lumbar total disc replacement with the CHARITE (TM) artificial disc versus lumbar fusion Part I: Evaluation of clinical outcomes

Maverick:

• Early removal of a Maverick disc prosthesis: surgical findings and morphological changes
• Clinical results of Maverick lumbar total disc replacement: two-year prospective follow-up

ProDisc:

• Lumbar total disc arthroplasty utilizing the ProDisc prosthesis in smokers versus nonsmokers: a prospective study with 2-year minimum follow-up
• Clinical results of total lumbar disc replacement with ProDisc II: three-year results for different indications.
• Total lumbar disc replacement: different results for different levels
• Results of the prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease
• Effect of intervertebral disc height on postoperative motion and outcomes after ProDisc-L lumbar disc replacement