Go Back   ISPINE.ORG Forum > Main forums > Abstracts and Articles
FAQ Members List Calendar Search Today's Posts Mark Forums Read

Abstracts and Articles Discuss Total lumbar disc replacement with ProDisc II: three-year results in the Main forums forums; From: PubMed. Spine. 2006 Aug 1;31(17):1923-32. Clinical results of total lumbar disc replacement with ProDisc II: ...

Reply
 
LinkBack Thread Tools Display Modes
  #1 (permalink)  
Old 06-26-2008, 07:08 AM
Senior Member
 
Join Date: May 2008
Posts: 196
Default Total lumbar disc replacement with ProDisc II: three-year results

From: PubMed. Spine. 2006 Aug 1;31(17):1923-32.

Clinical results of total lumbar disc replacement with ProDisc II: three-year results for different indications.
Siepe CJ, Mayer HM, Wiechert K, Korge A.

Abstract
Study Design: Prospective study analyzing midterm clinical results of total lumbar disc replacement (ProDisc II) for different indications. Objectives. To assess functional outcome after total lumbar disc replacement (TDR) treated for varying indications.
Summary of Background Data: Despite its frequent use and increasing popularity, indications and contraindications for TDR have not been defined precisely at this stage and remain a matter of debate, leading to disc replacement procedures in a variety of pathologies that have not yet been evaluated and compared separately.
Methods: Patients meeting inclusion criteria were evaluated prospectively according to Visual Analogue Scale ( VAS), Oswestry Questionnaire, SF-36, and numerous clinical parameters. Indications included degenerative disc disease (DDD), DDD with accompanying soft disc herniation ( nucleus pulposus prolapse, NPP), osteochondrosis following previous discectomy, and DDD with presence of Modic changes. Postoperative improvement was recorded and analyzed for influence of preoperative diagnosis.
Results: Overall, 92 patients from four groups with a mean follow-up of 34.2 months ( minimum, 24 months) achieved significant and maintained improvement from preoperative levels ( P < 0001). Patients with DDD + NPP achieved results significantly better than patients from the other groups (P < 0.05). Presence of Modic changes or previous discectomy did not influence outcome negatively. Improvement was achieved for both monosegmental and bisegmental disc replacements ( P < 0.05), nevertheless with significantly inferior results for bisegmental interventions at 12- and 24-month follow-up and considerably higher complication rate. While older patients were still highly satisfied with postoperative outcome, better functional outcome was observed in younger patients.
Conclusion: Present data suggest beneficial clinical results of TDR for treatment of DDD in a highly selected group of patients. Better functional outcome was obtained in younger patients under 40 years of age and patients with degenerative disc disease in association with disc herniation. Multilevel disc replacement had significantly higher complication rate and inferior outcome. Results are significantly dependent on preoperative diagnosis and patient selection, number of replaced segments, and age of the patient at the time of operation. Because of significantly varying outcomes, indications for disc replacement must be defined precisely

Keywords: MINIMUM FOLLOW-UP; ARTIFICIAL DISC; FUSION; ADJACENT; PROSTHESIS; SPINE; COMPLICATIONS; DEGENERATION; DISCOGRAPHY; SEGMENTS
Reply With Quote
Reply

Bookmarks

Thread Tools
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off
Trackbacks are On
Pingbacks are On
Refbacks are On



All times are GMT. The time now is 12:06 AM.


Powered by vBulletin® Version 3.7.2
Copyright ©2000 - 2024, Jelsoft Enterprises Ltd.