Articles & Abstracts Table of Contents

[iSpine Admin]

• Year -- All articles in descending order by date (most recent - least recent)

1. 2008
2. 2007
3. 2006-Earlier

• FDA Documentation -- FDA-related articles, organized by device

1. Charite
2. ProDisc

• Clinical Trial Data -- Articles involving clinical trials, organized by device

1. General
2. Bryan
3. Charite
4. Maverick
5. ProDisc

• Imaging -- Articles on imaging, organized by device

1. Charite
2. PCM

• Lumbar Artificial Disc Replacement -- Articles on lumbar ADR, organized by device

1. General
2. Charite
3. Maverick
4. ProDisc
5. Other Devices

• Cervical Artificial Disc Replacement

1. General
2. Bryan
3. ProDisc
4. Other

• Revision

1. General
2. CHARITE
3. Other

• Biologics

• Device Specific Studies

• Spine Articles

[iSpine Admin]

2008 - Articles from all categories listed in publication date order (newest on top):

• The importance of abnormal loading as a cause of low back pain

• Revision Strategies in Lumbar Total Disc Arthroplasty

• Intervertebral disc replacement for cervical degenerative disease

• Comparison of adverse events between the bryan artificial cervical disc and anterior cervical arthrodesis

• Determining factors that may affect outcome in lumbar total disc replacement.

• Revision surgery after implantation of a vertebral disc prosthesis

• Prevalence of lumbar total disc replacement candidates in a community-based spinal surgery practice

• Implications of lumbar plexus anatomy for removal of total disc replacements through a posterior approach

• A biomechanical study of artificial cervical discs using computer simulation

• What is the correlation of in vivo wear and damage patterns with in vitro TDR motion response?

• Wear of an experimental metal-on-metal artificial disc for the lumbar spine

• Effect of intervertebral disc height on postoperative motion and outcomes after ProDisc-L lumbar disc replacement

• Effect of age on clinical and radiographic outcomes and adverse events following 1-level lumbar arthroplasty

• Cervical kinematics after fusion and bryan disc arthroplasty

• Effect of position and height of a mobile core type artificial disc on the biomechanical behaviour of the lumbar spine

• Metal-on-metal artificial lumbar disc replacement: treatment of discogenic pain

• Patient selection for lumbar arthroplasty and arthrodesis: the effect of revision surgery

• Influence of the geometry of a ball-and-socket intervertebral prosthesis at the cervical spine

• Effects of a cervical disc prosthesis on maintaining sagittal alignment of the functional spinal unit and overall sagittal balance of the cervical spine

• Complications and reoperations of the SB Charité lumbar disc prosthesis

• Analysis of post-operative pain patterns following total lumbar disc replacement

• A comparison of two retroperitoneal surgical approaches for total disc arthroplasty of the lumbar spine

[iSpine Admin]

2007:

• Fentanyl Advisory

• ProDisc-C Receives FDA Approval

• FDA Approvable Letter Received

• Effect of uncovertebral joint excision on the motion response of the cervical spine after total disc replacement

• Comparative charge analysis of one- and two-level lumbar total disc arthroplasty versus circumferential lumbar fusion.

• The ability of diagnostic spinal injections to predict surgical outcomes

• The accuracy and validity of "Routine" X-rays in estimating lumbar disc arthroplasty placement

• In vivo evaluation of dynamic characteristics of the normal, fused, and disc replacement cervical spines

• Bryan artificial cervical disc arthroplasty in a patient with Klippel-Feil syndrome

• Acquired spondylolysis after implantation of a lumbar ProDisc II prosthesis

• An economic model of one-level lumbar arthroplasty versus fusion

• The ProDisc-C prothesis - Clinical and radiological experience

• Significantly improved lumbar arthroplasty placement using image guidance

• Posterior avulsion fracture at adjacent vertebral body during cervical disc replacement with ProDisc-C - A case report

• Comparison of biomechanical function at ideal and varied surgical placement for two lumbar artificial disc implant designs - Mobile-core Versus fixed-core

• Total lumbar disc replacement in athletes: clinical results, return to sport and athletic performance

• Range of motion change after cervical arthroplasty with ProDisc-C and Prestige artificial discs compared with anterior cervical discectomy and fusion

• Survival and clinical outcome of SB Charite III disc replacement for back pain

• Revision open anterior approaches for spine procedures

• Results of the prospective, randomized, multicenter FDA investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease

• Total lumbar disc replacement: different results for different levels

• Revision and explantation strategies involving the CHARITE lumbar artificial disc replacement

• Long-segment fusion of the thoracolumbar spine in conjunction with a motion-preserving artificial disc replacement

• CHARITE versus ProDisc - A comparative study of a minimum 3-year follow-up

• Long-term results of one-level lumbar arthroplasty: minimum 10-year follow-up of the CHARITE artificial disc in 106 patients

• US Clinical Trial Procedures Underway

• Magnetic resonance imaging clarity of the Bryan, Prodisc-C, Prestige LP, and PCM cervical arthroplasty devices

• Disc replacement using Pro-Disc C versus fusion: a prospective randomised and controlled radiographic and clinical study

• Release of cobalt and chromium ions into the serum following implantation of the metal-on-metal Maverick-type artificial lumbar disc (Medtronic Sofamor Danek)

• Early removal of a Maverick disc prosthesis

• Polyethylene wear and rim fracture in total disc arthroplasty

• Prevalence of heterotopic ossification following total disc replacement

• Polyethylene wear debris and long-term clinical failure of the Charité disc prosthesis

[iSpine Admin]

2006:

• Charité lumbar artificial disc retrieval: use of a lateral minimally invasive technique

• Access strategies for revision or explantation of the Charité lumbar artificial disc replacement

• Lumbar fusion outcomes in Washington State workers' compensation

• First Dynesys Hydroxyapatite-Coated Screws from Zimmer Spine Implanted in the United States and Europe

• Heterotopic ossification in total cervical artificial disc replacement

• Vascular complications of prosthetic inter-vertebral discs

• In vivo study of the kinematics in axial rotation of the lumbar spine after total intervertebral disc replacement

• [Stability of lumbar spine after artificial disc replacement]

• Biomechanical analysis of rotational motions after disc arthroplasty: implications for patients with adult deformities

• Clinical results of total lumbar disc replacement with ProDisc II: three-year results for different indications.

• Evaluation of surgical volume and the early experience with lumbar total disc replacement as part of the Investigational Device Exemption Study of the Charite Artificial Disc

• Porous coated motion cervical disc replacement: a biomechanical, histomorphometric, and biologic wear analysis in a caprine model.

• Finite element modeling of multi-level cervical spinal segments (C3-C6) and biomechanical analysis of an elastomer-type prosthetic disc.

• Revisability of the CHARITE artificial disc replacement: analysis of 688 patients enrolled in the U.S. IDE study of the CHARITE Artificial Disc

• Lumbar total disc arthroplasty utilizing the ProDisc prosthesis in smokers versus nonsmokers: a prospective study with 2-year minimum follow-up

• Computed tomography assessment of the accuracy of in vivo placement of artificial discs in the lumbar spine including radiographic and clinical consequences

• Treatment of symptomatic adjacent-segment degeneration after lumbar fusion with total disc arthroplasty by using the prodisc prosthesis

• Lumbar total disc arthroplasty in patients older than 60 years of age

• Early failure of lumbar disc replacement

• Charité total disc replacement--clinical and radiographical results.

• A review of the 2001 study: lumbar fusion versus nonsurgical treatment for chronic low back pain

2005:

• A prospective, randomized, multicenter FDA Investigational device exemptions study of lumbar total disc replacement with the CHARITE (TM) artificial disc versus lumbar fusion

• Complications and strategies for revision surgery in total disc replacement

• Clinical results of Maverick lumbar total disc replacement: two-year prospective follow-up

• Revision of a Charité artificial disc 9.5 years in vivo to a new Charité artificial disc: case report and explant analysis

• Analysis of operative complications in a series of 471 anterior lumbar interbody fusion procedures

• Vertical split fracture of the vertebral body following total disc replacement using ProDisc

2004:

• Complications and surgical revision for failed disc arthroplasty

2003:

• Biomechanical evaluation of total disc replacement arthroplasty

• General principles of total disc replacement arthroplasty

• The fate of the adjacent motion segments after lumbar fusion

• Partial disc replacement with the PDN prosthetic disc nucleus device

• Complications of artificial disc replacement with the SB Charité disc

• Video-assisted versus open anterior lumbar spine fusion surgery

2002:

• History, design and biomechanics of the LINK SB Charité artificial disc

2001:

• Lumbar fusion versus nonsurgical treatment for chronic low back pain

[iSpine Admin]

FOOD AND DRUG ADMINISTRATION DOCUMENTATION:

1. Charite

• A prospective, randomized, multicenter food and drug administration Investigational device exemptions study of lumbar total disc replacement with the CHARITE (TM) artificial disc versus lumbar fusion Part I: Evaluation of clinical outcomes
  
• Revisability of the CHARITE artificial disc replacement: analysis of 688 patients enrolled in the U.S. IDE study of the CHARITE Artificial Disc

1. ProDisc

• Results of the prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease
  

[iSpine Admin]

CLINICAL TRIALS

General:

• The myth of lumbar instability: the importance of abnormal loading as a cause of low back pain
• Significantly improved lumbar arthroplasty placement using image guidance: technical note
• Total lumbar disc replacement in athletes: clinical results, return to sport and athletic performance

Activ:

• US Clinical Trial Procedures Underway

Bryan:

• Effects of a cervical disc prosthesis on maintaining sagittal alignment of the functional spinal unit and overall sagittal balance of the cervical spine
• Intervertebral disc replacement for cervical degenerative disease--clinical results and functional outcome at two years in patients implanted with the Bryan cervical disc prosthesis

Charite:

• Effect of age on clinical and radiographic outcomes and adverse events following 1-level lumbar arthroplasty after a minimum 2-year follow-up
• Patient selection for lumbar arthroplasty and arthrodesis: the effect of revision surgery in a controlled, multicenter, randomized study
• Survival and clinical outcome of SB Charite III disc replacement for back pain
• Long-term results of one-level lumbar arthroplasty: minimum 10-year follow-up of the CHARITE artificial disc in 106 patients
• Prevalence of heterotopic ossification following total disc replacement. A prospective, randomized study of two hundred and seventy-six patients
• Polyethylene wear debris and long-term clinical failure of the Charité disc prosthesis: a study of 4 patients
• Revisability of the CHARITE artificial disc replacement: analysis of 688 patients enrolled in the U.S. IDE study of the CHARITE Artificial Disc
• Charité total disc replacement--clinical and radiographical results after an average follow-up of 17 years.
• A prospective, randomized, multicenter food and drug administration Investigational device exemptions study of lumbar total disc replacement with the CHARITE (TM) artificial disc versus lumbar fusion Part I: Evaluation of clinical outcomes

Maverick:

• Early removal of a Maverick disc prosthesis: surgical findings and morphological changes
• Clinical results of Maverick lumbar total disc replacement: two-year prospective follow-up

ProDisc:

• Lumbar total disc arthroplasty utilizing the ProDisc prosthesis in smokers versus nonsmokers: a prospective study with 2-year minimum follow-up
• Clinical results of total lumbar disc replacement with ProDisc II: three-year results for different indications.
• Total lumbar disc replacement: different results for different levels
• Results of the prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease
• Effect of intervertebral disc height on postoperative motion and outcomes after ProDisc-L lumbar disc replacement

[iSpine Admin]

CHARITE

• Revision and explantation strategies involving the CHARITE lumbar artificial disc replacement

• Revisability of the CHARITE artificial disc replacement: analysis of 688 patients enrolled in the U.S. IDE study of the CHARITE Artificial Disc

PCM

• Computed tomography assessment of the accuracy of in vivo placement of artificial discs in the lumbar spine including radiographic and clinical consequences

[iSpine Admin]

• Revision surgery after implantation of a vertebral disc prosthesis

• What is the correlation of in vivo wear and damage patterns with in vitro TDR motion response?

• Effect of age on clinical and radiographic outcomes and adverse events following 1-level lumbar arthroplasty

• Patient selection for lumbar arthroplasty and arthrodesis: the effect of revision surgery

• Complications and reoperations of the SB Charité lumbar disc prosthesis

• An economic model of one-level lumbar arthroplasty versus fusion

• Survival and clinical outcome of SB Charite III disc replacement for back pain

• Revision and explantation strategies involving the CHARITE lumbar artificial disc replacement

• CHARITE versus ProDisc - A comparative study of a minimum 3-year follow-up

• Long-term results of one-level lumbar arthroplasty: minimum 10-year follow-up of the CHARITE artificial disc in 106 patients

• Polyethylene wear and rim fracture in total disc arthroplasty

• Prevalence of heterotopic ossification following total disc replacement

• Polyethylene wear debris and long-term clinical failure of the Charité disc prosthesis

• Charité lumbar artificial disc retrieval: use of a lateral minimally invasive technique

• Access strategies for revision or explantation of the Charité lumbar artificial disc replacement

• Evaluation of surgical volume and the early experience with lumbar total disc replacement as part of the Investigational Device Exemption Study of the Charite Artificial Disc

• Revisability of the CHARITE artificial disc replacement: analysis of 688 patients enrolled in the U.S. IDE study of the CHARITE Artificial Disc

• Charité total disc replacement--clinical and radiographical results.

• A prospective, randomized, multicenter FDA Investigational device exemptions study of lumbar total disc replacement with the CHARITE (TM) artificial disc versus lumbar fusion

• Revision of a Charité artificial disc 9.5 years in vivo to a new Charité artificial disc: case report and explant analysis

• Biomechanical evaluation of total disc replacement arthroplasty

• General principles of total disc replacement arthroplasty

• Complications of artificial disc replacement with the SB Charité disc

• History, design and biomechanics of the LINK SB Charité artificial disc

[iSpine Admin]

• Revision Strategies in Lumbar Total Disc Arthroplasty

• Determining factors that may affect outcome in lumbar total disc replacement.

• Prevalence of lumbar total disc replacement candidates in a community-based spinal surgery practice

• Implications of lumbar plexus anatomy for removal of total disc replacements through a posterior approach

• Effect of position and height of a mobile core type artificial disc on the biomechanical behaviour of the lumbar spine

• Wear of an experimental metal-on-metal artificial disc for the lumbar spine

• The ability of diagnostic spinal injections to predict surgical outcomes

• The accuracy and validity of "Routine" X-rays in estimating lumbar disc arthroplasty placement

• Significantly improved lumbar arthroplasty placement using image guidance

• Comparison of biomechanical function at ideal and varied surgical placement for two lumbar artificial disc implant designs - Mobile-core Versus fixed-core

• Total lumbar disc replacement in athletes: clinical results, return to sport and athletic performance

• Revision open anterior approaches for spine procedures

• Long-segment fusion of the thoracolumbar spine in conjunction with a motion-preserving artificial disc replacement

• Lumbar fusion outcomes in Washington State workers' compensation

• Vascular complications of prosthetic inter-vertebral discs

• In vivo study of the kinematics in axial rotation of the lumbar spine after total intervertebral disc replacement

• [Stability of lumbar spine after artificial disc replacement]

• Biomechanical analysis of rotational motions after disc arthroplasty: implications for patients with adult deformities

• Computed tomography assessment of the accuracy of in vivo placement of artificial discs in the lumbar spine including radiographic and clinical consequences

• A review of the 2001 study: lumbar fusion versus nonsurgical treatment for chronic low back pain

[iSpine Admin]

• Release of cobalt and chromium ions into the serum following implantation of the metal-on-metal Maverick-type artificial lumbar disc (Medtronic Sofamor Danek)

• Early removal of a Maverick disc prosthesis

• Clinical results of Maverick lumbar total disc replacement: two-year prospective follow-up