Biologic disc treatments

[Crystal33]

A single injection promotes disc Regeneration

Hard to get medical industry to run with these treatments, when the huge money is to be made in ADR and fusion hardware.

CONCLUSION: The results of this study show the feasibility of restoring degenerative rabbit discs by a single injection of OP-1 into the nucleus pulposus. Importantly, the effects of the OP-1 injection on disc height were sustained for up to 24 weeks. The metabolic changes in the cells, following a single injection, might be sustained and, thus, induce long-term changes in disc structure. An efficacy study in large animals is required to show further that the intradiscal injection of OP-1, or bone morphogenetic proteins or growth factors with similar properties would be useful for the structural restoration of the IVD in humans.

Osteogenic protein-1 injection into a degenerated ... [Spine (Phila Pa 1976). 2006] - PubMed result

[Crystal33]

Red wine for disc degeneration.......

The Action of Resveratrol, a Phytoestrogen Found in Grapes,... : Spine

[Crystal33]

Have to add collagen type II to the list. A few human and numerous animal studies have shown that it significantly reduces joint pain. Combined with Glucosamine & Chondroitin seems to be superior to either alone.
It's something else that is not really heard about because there's no money in it to attract attention of big pharma or medical industry.
Could be worth a try for pain reduction. The following product sounds good, but i can't speak from experience.
ImmuCell Kolla2 Collagen Type ll 600mg 120 Capsules by Neocell Laboratories - $24.99

[Crystal33]

A recent study of restored disc height using non surgical decompression.

BioMed Central | Full text | Restoration of disc height through non-invasive spinal decompression is associated with decreased discogenic low back pain: a retrospective cohort study

[Rev. Zen]

The NuCore Injectable Nucleus seems very similar to the DASCOR System that is no longer viable. Is there any more information on the clinical trial in the US that is referenced?

[Crystal33]

Rev,
Nucore type procedure is 100+ times more desirable for patients but something seems to be holding back the development and introduction of minimal biological spine treatments. Could it be the threat to multi billion dollar fusion and ADR industries?

The images of regeneration you wont see with ADR or fusion.

CiteULike: An injectable nucleus replacement as an adjunct to microdiscectomy: 2 year follow-up in a pilot clinical study.

[wilsonrob]

Crystal,

I have had 2 ADR's at L4/5 and L5/S1. Now I have some problems with L3/4 with front thigh weakness and pain in back. I want to try the Biostat Fibrin sealant. Who performed this for you? Was it part of trial? Thanks